Mapping Rare and Common Causal Alleles for Complex Human Diseases
نویسندگان
چکیده
منابع مشابه
Mapping Rare and Common Causal Alleles for Complex Human Diseases
Advances in genotyping and sequencing technologies have revolutionized the genetics of complex disease by locating rare and common variants that influence an individual's risk for diseases, such as diabetes, cancers, and psychiatric disorders. However, to capitalize on these data for prevention and therapies requires the identification of causal alleles and a mechanistic understanding for how t...
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ژورنال
عنوان ژورنال: Cell
سال: 2011
ISSN: 0092-8674
DOI: 10.1016/j.cell.2011.09.011